The medical and healthcare industries rely heavily on biocompatible 3D printing materials for everything from surgical guides and patient-specific models to end-use devices. Two leading transparent, rigid, and biocompatible resins in the market are Liqcreate Bio-Med Clear and Formlabs BioMed Clear.
While both resins achieve the core goal—producing non-cytotoxic, non-sensitizing parts—their differing features, certifications, and compatibility models offer distinct benefits and drawbacks for different users. Although this article is written by Liqcreate, we try to give a fair comparison on these two materials, in order to know the strengths and weaknesses of each process.
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Comparing Liqcreate Bio-Med Clear and Formlabs BioMed Clear
In the table below you can find a 1-on-1 comparison of properties, sterilization tests validated and biocompatibility tests executed for each material anno November 2025.
| Property | Liqcreate Bio-Med Clear | Formlabs BioMed Clear |
| Biocompatibility | ISO 10993-5
ISO 10993-10 ISO 10993-23 |
ISO 10993-3
ISO 10993-5 ISO 10993-10 ISO 10993-11 ISO 10993-17 ISO 10993-18 |
| Tensile Strength | 50–60 MPa | 52 MPa |
| Flexural Strength | 89 MPa | 84 MPa |
| Flexural Modulus | 2200 MPa | 2300 MPa |
| Elongation at Break | 5-10 % | 12% |
| IZOD Notched impact | 28 J/m | 35 J/m |
| Sterilization methods tested | Autoclave 121 & 134C | Autoclave 121 & 134C
Ethylene Oxide Gamma E-beam |
| Compatible 3D-printers | Wide range of LCD, DLP and SLA
Printers must be open |
Formlabs 2,3,4 series |
Liqcreate Bio-Med Clear: The Open-Source Advantage
The primary strength of Liqcreate Bio-Med Clear is its open compatibility, which offers significant advantages for certain users:
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– Flexibility and Cost: Being an open material, it is compatible with a wide range of SLA, DLP, and LCD 3D printers, including lower-cost desktop models. This provides cost-saving opportunities and flexibility for organizations that do not rely exclusively on the Formlabs ecosystem.
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– Customization: Users with open-source printers have the ability to fine-tune printer parameters (exposure time, lift speed, etc.) to optimize the material’s performance for specific geometries or printing conditions.
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– Biocompatibility: It meets the fundamental biocompatibility requirements (Cytotoxicity, Sensitization, and Irritation), making it suitable for a broad array of medical devices, R&D, and custom components.
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– Autoclavable: The material is designed to withstand steam sterilization, a critical feature for surgical tools and devices used in sterile environments.
- – Price: With a material price of only €90,90 / kg it is much cheaper then any other biocompatibility material in the market.
Formlabs BioMed Clear: The Certified Ecosystem
Formlabs BioMed Clear leverages the strength of a fully integrated hardware/software/material ecosystem:
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– Premium Certification: The resin holds a USP Class VI certification, a more stringent standard that tests materials for biological reactivity. This is often required for pharmaceutical and drug delivery applications.
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– Integrated Quality Assurance: It is manufactured in an FDA-registered, ISO 13485-certified facility, providing a higher level of documentation for regulated medical device manufacturers.
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– Extended Contact Claims: Formlabs provides specific claims for long-term contact with skin and mucosal membranes, which is essential for wearables, long-term monitoring devices, and permanent airway components.
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– Reliability and Consistency: As a closed system material, Formlabs provides validated print settings on their printers to ensure consistent, reliable results, which is highly valued in regulated medical environments.
Potential Drawbacks
Liqcreate Bio-Med Clear Drawbacks
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– Validation Responsibility: While Liqcreate provides printing parameters, users must validate the other part of the workflow when using non-validated hardware (print settings, washing, and curing) on their specific open-source printer to ensure the final part meets all standards.
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– Lower Barrier to Entry: Because it is used on a variety of machines, the final part quality and mechanical properties can vary significantly if the user does not follow the post-processing instructions precisely.
Formlabs BioMed Clear Drawbacks
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– System Lock-In: The resin is proprietary and primarily restricted to Formlabs printers. This higher barrier to entry requires significant initial investment in the Formlabs ecosystem (printer, automated post-processing units, specific tanks).
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– Higher Cost per Kilogram: This resin generally command a higher price than third-party alternatives, increasing the material cost per part.
Conclusion: Choosing the Right Biocompatible Resin
The choice between Liqcreate Bio-Med Clear and Formlabs BioMed Clear depends entirely on your application and your existing 3D printing infrastructure:
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– Choose Formlabs BioMed Clear when your application requires USP Class VI certification, long-term contact claims, or if you operate within a highly regulated environment (like a hospital or FDA-registered manufacturing facility) where the simplicity and consistency of a closed, validated ecosystem are critical.
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– Choose Liqcreate Bio-Med Clear if: You own an open-source DLP/LCD/SLA printer (and need to print biocompatible parts), you require steam sterilization (autoclaving), or you have the technical expertise to validate your custom post-processing workflow to meet the necessary medical standards.
Ultimately, each option has its own set of customers, but Formlabs offers a higher degree of regulatory assurance due to its controlled ecosystem, while Liqcreate offers greater versatility and accessibility across different hardware platforms.
Liqcreate Bio-Med Clear
Liqcreate Bio-Med Clear is a rigid clear biocompatble photopolymer resin and can be processed on most resin based 3D-printers. 3D-printed parts from this material exhibit biocompatible properties when post processed according to the processing instructions1. After washing and post-curing according to the instructions, printed parts from Liqcreate Bio-Med Clear pass the biocompatibility tests of:
| Â Â Â â—‹Â Â Cytotoxicity | ISO 10993-5:2009 |
| Â Â Â â—‹Â Â Sensitization | ISO 10993-10:2021 |
| Â Â Â â—‹Â Â Irritation | ISO 10993-23:2021 |
Printed parts from Bio-Med Clear can be disinfected with commonly used disinfectants and sterilized by steam sterilization using an autoclave.
Key benefits |
3D-Printer compatibility |
| ·       Biocompatible | ·       Asiga series |
| ·       Steam sterilization possible | ·    Phrozen series |
| ·       High accuracy | ·    Elegoo & Anycubic series |
| ·       Dimensional stable | ·    And many more |


